RESEARCH PAPER
HYDROCOLLOID DRESSING FOR DIAPER DERMATITIS IN NEONATES AND YOUNG INFANTS HOSPITALIZED IN NEONATAL INTENSIVE CARE UNITS:
A QUASI-EXPERIMENTAL STUDY
1
Department of Child Development, Faculty of Health Sciences, Istanbul Beykent University, Istanbul, Türkiye
2
Department of Pediatric Nursing, Florence Nightingale Faculty of Nursing, Istanbul University – Cerrahpasa, Istanbul, Türkiye
Submission date: 2025-09-22
Final revision date: 2025-11-04
Acceptance date: 2025-11-18
Publication date: 2025-11-21
KEYWORDS
TOPICS
ABSTRACT
Background:
Diaper dermatitis (DD) is among the most frequent dermatological problems in neonates and young infants, particularly in neonatal intensive care units (NICUs). This study aimed to examine the effect of hydrocolloid dressing on the healing process of DD.
Material and methods:
A quasi-experimental controlled trial was conducted with 44 infants hospitalized in a NICU and diagnosed with DD (intervention group = 22; control group = 22). The intervention group received a hydrocolloid dressing, whereas the control group received a barrier cream containing 40% zinc oxide. The severity of DD was assessed using the Clinical Evaluation Scale for DD at baseline and at 24, 48, and 72 hours after care.
Results:
Infants treated with hydrocolloid dressing had significantly lower mean DD scores at 24, 48, and 72 hours compared with those treated with zinc oxide cream (all p<0.001). The intervention group also demonstrated a significantly shorter healing time (p<0.001).
Conclusions:
Hydrocolloid dressing was associated with faster improvement and shorter healing duration compared with zinc oxide cream in infants hospitalized in the NICU. Further randomized and blinded studies with larger samples are warranted to confirm these findings.
Diaper dermatitis (DD) is among the most frequent dermatological problems in neonates and young infants, particularly in neonatal intensive care units (NICUs). This study aimed to examine the effect of hydrocolloid dressing on the healing process of DD.
Material and methods:
A quasi-experimental controlled trial was conducted with 44 infants hospitalized in a NICU and diagnosed with DD (intervention group = 22; control group = 22). The intervention group received a hydrocolloid dressing, whereas the control group received a barrier cream containing 40% zinc oxide. The severity of DD was assessed using the Clinical Evaluation Scale for DD at baseline and at 24, 48, and 72 hours after care.
Results:
Infants treated with hydrocolloid dressing had significantly lower mean DD scores at 24, 48, and 72 hours compared with those treated with zinc oxide cream (all p<0.001). The intervention group also demonstrated a significantly shorter healing time (p<0.001).
Conclusions:
Hydrocolloid dressing was associated with faster improvement and shorter healing duration compared with zinc oxide cream in infants hospitalized in the NICU. Further randomized and blinded studies with larger samples are warranted to confirm these findings.
REFERENCES (15)
1.
Zakharova IN, Zaytseva OV, Fedenko ES, Pampura AN, Murashkin NN, Pupykina VV. The role of emollients is a plus in diaper dermatitis. Meditsinskiy Sovet = Medical Council. 2025; 11: 123-132. https://doi.org/10.21518/ms202....
2.
Esser MS, Ngui EM, Johnson TS. Contributing factors to diaper dermatitis and NICU length of stay. Journal of Neonatal Nursing. 2021; 27(5): 358-364. https://doi.org/10.1016/J.JNN.....
3.
Helms LE, Burrows HL. Diaper dermatitis. Pediatr Rev. 2021; 42(1): 48-50. https://doi.org/10.1542/PIR.20....
4.
Stamatas GN, Tierney NK. Diaper dermatitis: etiology, manifestations, prevention, and management. Pediatr Dermatol. 2014; 31(1): 1-7. https://doi.org/10.1111/pde.12....
5.
Gupta P, Nagesh K, Garg P, Thomas J, Suryawanshi P, Sethuraman G, et al. Evidence-based consensus recommendations for skin care in healthy, full-term neonates in India. Pediatric Health Med Ther. 2023; 2023(14): 249-265. https://doi.org/10.2147/PHMT.S....
6.
Brandon D, Hill C, Heimall L. Neonatal skin care: evidence-based clinical practice guidelines. Vol. 4. Washington DC: Association of Women’s Health, Obstetric and Neonatal Nurses; 2018.
7.
Alzain AS, Althobaiti IA, Aljameeli HB, Albahrani AR, Hajie Alrizq S, Alghamdi SO. Advancements in wound care nursing: a review of innovative dressings and techniques. Journal of Healthcare Sciences. 2024; 4(12): 1016-1023. https://doi.org/10.52533/johs.....
8.
Qiao XP, Ge YZ. Clinical effect of hydrocolloid dressings in prevention and treatment of infant diaper rash. Exp Ther Med. 2016; 12(6): 3665-3669. https://doi.org/10.3892/etm.20....
9.
Giacaman A, Boix-Vilanova J, Martín-Santiago A. Hydrocolloid dressing for the treatment of severe diaper dermatitis. Pediatr Dermatol. 2023; 40(1): 224-225. https://doi.org/10.1111/pde.15....
10.
Gözen D, Çağlar S, Bayraktar S, Atıcı F. Diaper dermatitis care of newborns human breast milk or barrier cream. J Clin Nurs. 2013; 23(3-4): 515-523. https://doi.org/10.1111/jocn.1....
11.
Seifi B, Jalali S, Heidari M. Assessment effect of breast milk on diaper dermatitis. Dermatol Reports. 2017; 9(1): 17-20. https://doi.org/10.4081/dr.201....
12.
Başkale H, Çelik SN. The effect of topical application of breast milk and education on preventing diaper dermatitis in children in rural areas. J Pediatr Nurs. 2024; 75: e169-175. https://doi.org/10.1016/J.PEDN....
13.
Brodbeck A, Esser MS, Jacobson E, Helminiak G, Islas D. Topical use of human milk in the neonatal intensive care unit an integrative review. Advances in Neonatal Care. 2024; 24(1): 78-85. https://doi.org/10.1097/ANC.00....
14.
Sharifi-Heris Z, Farahani LA, Haghani H, Abdoli-Oskouee S, Hasanpoor-Azghady SB. Comparison the effects of topical application of olive and calendula ointments on children’s diaper dermatitis: a triple-blind randomized clinical trial. Dermatol Ther. 2018; 31: e12731. https://doi.org/10.1111/dth.12....
15.
O’Connor RJ, Visscher MO, Narendran V, Wang Y, Wiesemann F, Carr AN. Clinical evaluation of a diaper containing a shea butter-based emollient and impact on diapered skin erythema. Pediatr Dermatol. 2025; 42(3): 532-538. https://doi.org/10.1111/pde.15....
| eISSN: | 2354-0265 |
| ISSN: | 2353-6942 |
We process personal data collected when visiting the website. The function of obtaining information about users and their behavior is carried out by voluntarily entered information in forms and saving cookies in end devices. Data, including cookies, are used to provide services, improve the user experience and to analyze the traffic in accordance with the Privacy policy. Data are also collected and processed by Google Analytics tool (more).
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
