REVIEW PAPER
Sudden cardiac arrest and sudden cardiac death in athletes: an updated perspective
 
More details
Hide details
1
Lower Silesia Center of Oncology, Pulmonology, and Hematology, Wrocław, Poland
 
2
Faculty of Medicine, Wroclaw Medical University, Wrocław, Poland
 
 
Submission date: 2026-03-04
 
 
Final revision date: 2026-04-08
 
 
Acceptance date: 2026-04-10
 
 
Online publication date: 2026-04-17
 
 
Corresponding author
Rafał Wilczyński   

Lower Silesia Center of Oncology, Pulmonology, and Hematology, Plac Ludwika Hirszfelda 12, 53-413 Wrocław, Poland
 
 
 
KEYWORDS
TOPICS
ABSTRACT
Sudden cardiac arrest (SCA) and sudden cardiac death (SCD) in athletes are rare but catastrophic events that generate substantial medical, ethical, and public health concern. Although regular physical activity is associated with significant cardiovascular benefits, intense training and competition may unmask underlying structural or electrical heart diseases in susceptible individuals. The most common causes of SCA and SCD in young athletes include hypertrophic cardiomyopathy, arrhythmogenic cardiomyopathy, left ventricular hypertrophy, myocarditis, congenital coronary artery anomalies, and primary electrical disorders such as long QT syndrome. In athletes over 35 years of age, asymptomatic atherosclerotic cardiovascular disease predominates. Pre-participation cardiovascular screening, including medical history, physical examination, and, in some regions, electrocardiography (ECG) aims to identify individuals at risk. However, controversy persists regarding the sensitivity, specificity, cost-effectiveness, and potential for false-positive findings associated with screening strategies. Rapid recognition of SCA, immediate cardiopulmonary resuscitation, and early defibrillation with automated external defibrillators (AEDs) remain critical determinants of survival. The aim of this review is to summarize current evidence on the epidemiology, risk stratification, screening strategies, and emergency management of SCA and SCD in athletes and to highlight ongoing challenges and areas for future research.
REFERENCES (50)
1.
Pelliccia A, Sharma S, Gati S, Bäck M, Börjesson M, Caselli S, et al. 2020 ESC Guidelines on sports cardiology and exercise in patients with cardiovascular disease: The Task Force on sports cardiology and exercise in patients with cardiovascular disease of the European Society of Cardiology (ESC). Eur Heart J. 2021;42(1):17-96. https://doi.org/10.1093/eurhea....
 
2.
World Health Organization. WHO guidelines on physical activity and sedentary behaviour. Geneva: World Health Organization; 2020.
 
3.
Landry CH, Allan KS, Connelly KA, Cunningham K, Morrison MJ, Dorian P. Sudden Cardiac Arrest during Participation in Competitive Sports. N Engl J Med. 2017; 377(20): 1943-1953. https://doi.org/10.1056/NEJMoa....
 
4.
Malik A, Hanson J, Han J, Dolezal B, Bradfield J, Boyle NG, et al. Sudden cardiac arrest in athletes and strategies to optimize preparedness. Clin Cardiol. 2023; 46(9): 1059-1071. https://doi.org/10.1002/clc.24....
 
5.
Petek BJ, Churchill TW, Moulson N, Delong R, Minnig MC, Kliethermes SA, et al. Survival outcomes after sudden cardiac arrest in young competitive athletes from the United States. J Am Coll Cardiol. 2025; 85(17): 1682-1692. https://doi.org/10.1016/j.jacc....
 
6.
Kim JH, Rim AJ, Miller JT, Jackson M, Patel N, Rajesh S, et al. Cardiac arrest during long-distance running races. JAMA. 2025; 333(19): 1699-1707. https://doi.org/10.1001/jama.2....
 
7.
Sgarro GA, Vasco P, Santoro D, Grilli L, Giglio M, Brunetti ND, et al. Identifying risk patterns for sudden cardiac death in athletes: a clustering and principal component analysis approach. PLoS One. 2026; 21(1): e0339377. https://doi.org/10.1371/journa....
 
8.
Drezner JA, Toresdahl BG, Rao AL, Huszti E, Harmon KG. Outcomes from sudden cardiac arrest in US high schools: a 2-year prospective study from the National Registry for AED Use in Sports. Br J Sports Med. 2013; 47(18): 1179-1183. https://doi.org/10.1136/bjspor....
 
9.
Egger F, Scharhag J, Kästner A, Dvořák J, Bohm P, Meyer T. FIFA Sudden Death Registry (FIFA-SDR): a prospective, observational study of sudden death in worldwide football from 2014 to 2018. Br J Sports Med. 2022; 56(2): 80-87. https://doi.org/10.1136/bjspor....
 
10.
Petek BJ, Churchill TW, Moulson N, Kliethermes SA, Baggish AL, Drezner JA, et al. Sudden cardiac death in National Collegiate Athletic Association athletes: a 20-year study. Circulation. 2024; 149(2): 80-90. https://doi.org/10.1161/CIRCUL....
 
11.
Kim JH, Martinez MW, Guseh JS, Krishnan S, Gray B, Harmon KG, et al. A contemporary review of sudden cardiac arrest and death in competitive and recreational athletes. Lancet. 2024; 404(10468): 2209-2222. https://doi.org/10.1016/S0140-....
 
12.
Lampert R, Harmon KG. Sports-related sudden death in the general population. N Engl J Med. 2026; 394: 268-280. https://doi.org/10.1056/NEJMra....
 
13.
Miguel Gonçalves C, Vazão A, Carvalho M, Cabral M, Martins A, Martins H, et al. Sudden cardiac death in athletes: a 20-year analysis in Portugal. Rev Port Cardiol. 2025; 44(2): 77-83. https://doi.org/10.1016/j.repc....
 
14.
Astley C, Petek BJ, Delong RN, Kucera KL, Goettsch BP, Harmon KG, et al. Sudden cardiac arrest among young competitive athletes before and during the COVID-19 pandemic. JAMA Netw Open. 2025; 8(2): e2461327. https://doi.org/10.1001/jamane....
 
15.
Gobeil K, Lampert R. Sports related sudden cardiac arrest in the older athlete: don’t retire the running shoes!. J Am Coll Cardiol EP. 2023; 9(7 Pt 1): 904-906. https://doi.org/10.1016/j.jace....
 
16.
Marijon E, Bougouin W, Karam N, Beganton F, Lamhaut L, Perrier MC, et al. Survival from sports-related sudden cardiac arrest: in sports facilities versus outside of sports facilities. Am Heart J. 2015; 170(2): 339-345.e1. https://doi.org/10.1016/j.ahj.....
 
17.
Visanji M, Allan KS, Charette M, Grunau B, Roy C, Goldstein J, et al. Sports-related sudden cardiac arrest in canada: incidence and survival. Can J Cardiol. 2025; 41(3): 522-530. https://doi.org/10.1016/j.cjca....
 
18.
Yano S, Katsumata Y, Muramoto Y, Kinoda A, Kimura T, Sato K, et al. Characteristics of sudden cardiac arrest in young athletes: a web-based survey of athletes in Japanese college sports. Cardiol. Res. Pract. 2025; (1): 1265728. https://doi.org/10.1155/crp/12....
 
19.
Bohm P, Scharhag J, Meyer T. Data from a nationwide registry on sports-related sudden cardiac deaths in Germany. Eur J Prev Cardiol. 2016; 23(6): 649-656. https://doi.org/10.1177/204748....
 
20.
Finocchiaro G, Westaby J, Sheppard MN, Papadakis M, Sharma S. Sudden cardiac death in young athletes: JACC state-of-the-art review. J Am Coll Cardiol. 2024; 83(2): 350-370. https://doi.org/10.1016/j.jacc....
 
21.
Weizman O, Empana JP, Blom M, Tan HL, Jonsson L, Narayanan K, et al. Incidence of cardiac arrest during sports among women in the European Union. J Am Coll Cardiol. 2023; 81(11): 1021-1031. https://doi.org/10.1016/j.jacc....
 
22.
Han J, Lalario A, Merro E, Sinagra G, Sharma S, Papadakis M, et al. Sudden cardiac death in athletes: facts and fallacies. J Cardiovasc Dev Dis. 2023; 10(2): 68. https://doi.org/10.3390/jcdd10....
 
23.
Finocchiaro G, Papadakis M, Robertus JL, Dhutia H, Steriotis AK, Tome M, et al. Etiology of sudden death in sports: insights from a United Kingdom Regional Registry. J Am Coll Cardiol. 2016; 67(18): 2108-2115. https://doi.org/10.1016/j.jacc....
 
24.
Manabe T, Kato J, Yamasawa F. Sudden cardiac arrest during marathons among young, middle-aged, and senior runners. Resuscitation. 2024; 204: 110415. https://doi.org/10.1016/j.resu....
 
25.
Seely KD, Crockett KB, Nigh A. Sudden cardiac death in a young male endurance athlete. J Osteopath Med. 2023; 123(10): 461-465. https://doi.org/10.1515/jom-20....
 
26.
Arzayus-Patiño L, Carabali-Bonilla YF, Mora-Salazar MC, Gómez CC, Benavides-Cordoba V. Cardiovascular diseases and risk factors associated with sudden cardiac death in amateur athletes: a scoping review. Front. Public Health. 2026; 14: 1770168. https://doi.org/10.3389/fpubh.....
 
27.
Malhotra A, Dhutia H, Finocchiaro G, Gati S, Beasley I, Clift P, et al. Outcomes of cardiac screening in adolescent soccer players. N Engl J Med. 2018; 379(6): 524-534. https://doi.org/10.1056/NEJMoa....
 
28.
Muchaili L, Liwleya S, Siame L, Nzobokela J, Machacha B, Sinamwenda EN, et al. Atherosclerosis and sudden cardiac death in athletes. Current Problems in Cardiology. 2025; 50(9): 103123. https://doi.org/10.1016/j.cpca....
 
29.
Finocchiaro G, Radaelli D, D’Errico S, Bhatia R, Papadakis M, Behr ER, et al. Ethnicity and sudden cardiac death in athletes: insights from a large United Kingdom registry. Eur J Prev Cardiol. 2024; 31(12): 1518-1525. https://doi.org/10.1093/eurjpc....
 
30.
Finocchiaro G, Radaelli D, Johnson D, Bhatia RT, Westaby J, D’Errico S, et al. Yield of molecular autopsy in sudden cardiac death in athletes: data from a large registry in the UK. Europace. 2024; 26(2): euae029. https://doi.org/10.1093/europa....
 
31.
Harmon KG, Zigman M, Drezner JA. The effectiveness of screening history, physical exam, and ECG to detect potentially lethal cardiac disorders in athletes: a systematic review/meta-analysis. J Electrocardiol. 2015; 48(3): 329-338. https://doi.org/10.1016/j.jele....
 
32.
Banerjee A. Cardiovascular evaluation of athletes ahead of participation. Front Cardiovasc Med. 2025; 12: 1666981. https://doi.org/10.3389/fcvm.2....
 
33.
Maron BJ, Haas TS, Doerer JJ, Thompson PD, Hodges JS. Comparison of U.S. and Italian experiences with sudden cardiac deaths in young competitive athletes and implications for preparticipation screening strategies. Am J Cardiol. 2009; 104(2): 276-280. https://doi.org/10.1016/j.amjc....
 
34.
Westaby J, Sheppard MN. Epidemiology and aetiology of sudden cardiac death in athletes. Br J Cardiol. 2025; 32: 49-52. https://doi.org/10.5837/bjc.20....
 
35.
Sheppard MN, Westaby J, Zullo E, Fernandez BVE, Cox S, Cox A. Sudden arrhythmic death and cardiomyopathy are important causes of sudden cardiac death in the UK: results from a national coronial autopsy database. Histopathology. 2023; 82(7): 1056-1066. https://doi.org/10.1111/his.14....
 
36.
Finocchiaro G, Radaelli D, D’Errico S, Papadakis M, Behr ER, Sharma S, et al. Sudden cardiac death among adolescents in the United Kingdom. J Am Coll Cardiol. 2023; 81(11): 1007-1017. https://doi.org/10.1016/j.jacc....
 
37.
Zerbo S, Albano GD, Malta G, Alongi A, Maresi E, Argo A. Sudden cardiac death in a young athlete due to anomalous origin of both coronaries from a common ostium. Forensic Sci Med Pathol. 2025; 21(3): 1540-1545. https://doi.org/10.1007/s12024....
 
38.
Smith CM, Moore F, Drezner JA, Aird R. Resuscitation on the field of play: a best-practice guideline from Resuscitation Council UK. Br J Sports Med. 2024; 58(19): 1098-1106. https://doi.org/10.1136/bjspor....
 
39.
Michelland L, Murad MH, Bougouin W, Van Der Broek M, Prokop LJ, Anys S, et al. Association between basic life support and survival in sports-related sudden cardiac arrest: a meta-analysis. Eur Heart J. 2023; 44(3): 180-192. https://doi.org/10.1093/eurhea....
 
40.
Dickey GJ, Dorian P, Fedder SP, Patel J, Shin S, Shore E, et al. Revisiting commotio cordis: novel insight into clinical variability, diagnosis, epidemiology, and prevention. J Am Heart Assoc. 2026; 15(5). https://doi.org/10.1161/JAHA.1....
 
41.
Spitaler P, Stühlinger M, Adukauskaite A, Bauer A, Dichtl W. A soccer shot with lengthy consequences-case report & current literature review of commotio cordis. J Clin Med. 2023; 12(6): 2323. https://doi.org/10.3390/jcm120....
 
42.
Shore E, Moseley GA, DeLong R, Register-Mihalik J, Drezner JA, Dickey GJ, et al. Incidents and patterns of commotio cordis among athletes in the USA from 1982 to 2023. Inj Prev. 2026; 32: 329-334.https://doi.org/10.1136/ip-202....
 
43.
Ghani U, Farooq O, Alam S, Khan MJ, Rahim O, Rahim S. Sudden cardiac death in athletes: consensuses and controversies. Cureus. 2023; 15(6): e39873. https://doi.org/10.7759/cureus....
 
44.
Peng T, Derry LT, Yogeswaran V, Goldschlager NF. Commotio cordis in 2023. Sports Med. 2023; 53(8): 1527-1536. https://doi.org/10.1007/s40279....
 
45.
Salzillo C, Marzullo A. Commotio cordis in sudden cardiac death in the young: a state-of-the-art review. Rev Cardiovasc Med. 2025; 26(9): 43357. https://doi.org/10.31083/RCM43....
 
46.
Maron BJ, Gohman TE, Kyle SB, Estes NA 3rd, Link MS. Clinical profile and spectrum of commotio cordis. JAMA. 2002;287(9):1142-1146. https://doi.org/10.1001/jama.2....
 
47.
Lee RN, Sampaio Rodrigues T, Gan JT, Han HC, Mikhail R, Sanders P, et al. Commotio cordis in non-sport-related events: a systematic review. JACC Clin Electrophysiol. 2023; 9(8 Pt 1): 1321-1329. https://doi.org/10.1016/j.jace....
 
48.
Melo L, Patail H, Sharma T, Frishman WH, Aronow WS. Commotio cordis: a comprehensive review. Cardiol Rev. 2025; 33(3): 256-259. https://doi.org/10.1097/CRD.00....
 
49.
Dickey GJ, Bian K, Islam SU, Khan HR, Rohr S, Mao H. Advancing commotio cordis safety standards using the Total Human Models for Safety (THUMS). Ann Biomed Eng. 2023; 51(9): 2070-2085. https://doi.org/10.1007/s10439....
 
50.
Okorare O, Alugba G, Olusiji S, Evbayekha EO, Antia AU, Daniel E, et al. Sudden cardiac death: an update on commotio cordis. Cureus. 2023; 15(4): e38087. https://doi.org/10.7759/cureus....
 
eISSN:2354-0265
ISSN:2353-6942
Journals System - logo
Scroll to top